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Archiver > GENEALOGY-DNA > 2003-03 > 1046628240


From: "John F. Chandler" <>
Subject: Re: [DNA] Mutation Rates autosomal STR's
Date: Sun, 2 Mar 2003 13:04 EST
In-Reply-To: ncuster@mcn.org message <003701c2e05a$0c75f250$98c94dd1@NancySonyIV> of Sat, 1 Mar 2003 18:21:26 -0700


Nancy wrote:
> what I thought was really interesting was a noticeable difference in
> mutation rates between the same markers in maternal and paternal
> meioses. For example, marker FGA (on chromosome 4) had an apparent
> mutation rate of 0.01 in maternal meioses and 0.29 in paternal meioses.

I'm skeptical. There is a factor that may not have been sufficiently
taken into account, namely, false positive results for paternity. In
other words, those men may not have been the fathers after all, and so
the discrepancies were not "mutations".

John Chandler


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