GENEALOGY-DNA-L Archives

From: "Nancy Custer" <>
Subject: RE: [DNA] Mutation Rates autosomal STR's
Date: Sun, 2 Mar 2003 10:18:04 -0800
In-Reply-To: <JCHBN.030302.130426.RC0@CUVMB.CC.COLUMBIA.EDU>

Yes, it would be interesting to know how many mutations per man. N

-----Original Message-----
From: John F. Chandler [mailto:]
Sent: Sunday, March 02, 2003 10:04 AM
To:
Subject: Re: [DNA] Mutation Rates autosomal STR's

Nancy wrote:
> what I thought was really interesting was a noticeable difference in
> mutation rates between the same markers in maternal and paternal
> meioses. For example, marker FGA (on chromosome 4) had an apparent
> mutation rate of 0.01 in maternal meioses and 0.29 in paternal
meioses.

I'm skeptical. There is a factor that may not have been sufficiently
taken into account, namely, false positive results for paternity. In
other words, those men may not have been the fathers after all, and so
the discrepancies were not "mutations".

John Chandler


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This thread:

• [DNA] Mutation Rates autosomal STR's by "Nancy Custer" <>
  • Re: [DNA] Mutation Rates autosomal STR's by "John F. Chandler" <>

    • RE: [DNA] Mutation Rates autosomal STR's by "Nancy Custer" <>