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From:
Subject: Re: [DNA] Marker Mutation Rates [and MRCA]
Date: Mon, 3 Nov 2003 20:19:59 -0500 (EST)
References: <20031103154317.91051.qmail@web11404.mail.yahoo.com>
In-Reply-To: <20031103154317.91051.qmail@web11404.mail.yahoo.com> (messagefrom Mike Humphrey on Mon, 3 Nov 2003 07:43:17 -0800 (PST))


Mike wrote:
> I'm very happy to see this recent MCRA discussion. During the past 7 months
> since I started reading this list, I've been struck by the wide variance in
> observed mutation rates in several surname projects. E.G., Doug Mumma's
> excellent study in which he saw rates faster than .002.

The Mumma study saw two things: one an average mutation rate about 0.0027,
and the other an UPPER BOUND about 0.004. The upper bound got the most
attention, but it is not very useful to compare an extremum from one
study with the mean from another.

John Chandler


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