GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2003-11 > 1067993589
Subject: Re: [DNA] mtDNA in Laci Peterson case [FBI database]
Date: Tue, 4 Nov 2003 19:53:09 EST
In a message dated 11/04/03 1:30:48 PM Pacific Standard Time,
> I find it hard to believe that 1 out of 122 random mt DNA samples would
> have the
> same sequence as Laci and her mother.
Actually, it's quite possible, especially if Laci had the most common
haplotype for Haplogroup H (no mutations in HVR1 and the very common 263G in HVR2).
The minimal requirements for adding records to the FBI database are completion
of 16024-16365 for HVR1 and 73-340 for HVR2. I don't know whether their
current forensic work covers more bases.
Here's a link to another article with a defense witness claiming her
haplotype could be found in 1 out of 11. That IS about the frequency of the CRS in
some European populations when considering only HVR1 -- I don't know how much the
numbers drop when you add HVR2, though. List members who report multiple
low-resolution (HVR1) matches from FTDNA also report many fewer high-resolution
matches. But that could be an artefact if few people have ordered the
Many haplotypes are much, much rarer than the CRS. In fact, list members have
shared haplotypes which don't show up in databases with thousands of records.
I downloaded the FBI database and software when it first came online about a
year and a half ago. I played around with it some, but I wasn't convinced I
was setting the parameters correctly, so I abandoned the effort. Maybe it's time
to revisit this, if some list members are feeling ambitious.
Ann Turner - GENEALOGY-DNA List Administrator
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