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Archiver > GENEALOGY-DNA > 2010-11 > 1290288275


From: Robert Stafford <>
Subject: Re: [DNA] FW: Odds Are, It's Wrong - 5% of the time
Date: Sat, 20 Nov 2010 15:24:35 -0600
References: <F9C440A2-FC59-4A9E-AAAC-85DEE9D2FAB0@GMAIL.COM><COL115-W50D879F102DC3996D9D454A03A0@phx.gbl><4CE7A3C0.7050702@ucl.ac.uk><COL115-W1464B78AF0292D6AEFA183A03B0@phx.gbl><COL115-W5950BB2C58A31B4806036EA03B0@phx.gbl><4CE8088B.3020500@ucl.ac.uk>
In-Reply-To: <4CE8088B.3020500@ucl.ac.uk>


I am not sure how this applies to TMRCA calculations. What is the null
hypothesis you are testing? What do the Bayesians use as the confidence
interval for TMRCA?

Bob Stafford

On Sat, Nov 20, 2010 at 11:42 AM, James Heald <> wrote:

> On 20/11/2010 13:35, Steven Bird wrote:
>
>
> This issue has implications in TMRCA estimation. People sometimes use
> Frequentist confidence intervals to give a range estimate of potentially
> plausible TMRCAs -- ie they find the TMRCA for which obtaining n
> mutations or fewer would only occur with a probability of 0.05
>
>


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