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Archiver > WEBB > 2003-09 > 1064096207


From: yvette white <>
Subject: Re: [WEBB] A LOOK at my WEBB DNA Study aggregate results so far
Date: Sat, 20 Sep 2003 15:16:54 -0700 (PDT)
In-Reply-To: <113.28e5afd5.2c9dbe51@aol.com>


Anne, you got layman's terms for all that?

yvette

wrote:
For those of you interested in the technical results, I have prepared this
update. I found it very interesting, although I have little understanding of
what practical results it might have. For those of you with more knowledge than
I have, I would like feedback on the WEBB 25 marker value analysis -- do the
results suggest anything to any of you?

For those of you with even less knowledge than my meagre bits, you might find
the following reading useful:
DNA 101 http://blairgenealogy.com/dna/dna101.html

PRELIMINARY ANALYSIS
WEBB Surname Unique 12 marker strings
Ordered by value in DYS#
(DYS means DNA Y-chromosome Segment)

DYS# (in order. left to right under "Result Strings")
393,390,19(394),391,385a,385b,426,388,439,389-1,392,389-1
1st 2nd 3rd 4 5 6 7 8 9
10 11 12

No. of Result Strings
Group
Participants M M M
"Name"* MS
1 13 22 14 10 13 14 11 13 11 12 11 28 G
N
1 13 24 14 11 11 14 12 12 12 13 13 29 F
Y-13
1 13 24 14 11 11 14 12 12 12 14 13 30 E
Y- 5
1 13 24 14 11 11 14 12 12 13 13 13 29 D
Y- 6
1 13 24 15 11 11 14 12 12 13 13 13 29 C
N
3 13 24 15 11 11 14 12 12 13 13 13 30 A
N
2 14 22 14 10 13 13 11 14 12 13 11 29 B
N
*Arbitrarily assigned for purposes of easier discussion

M = these markers have been found to mutate at a slightly higher rate than
others
MS = has been found to occur in multiple surnames in a study by Blair of 1386
participants in 66 different surname groups. 83 out of a total of 620 12
marker combinations had multiple surnames, 505 participants.
N No occurrence of multiple surnames with this string
Y Yes
# Number of Surnames
F had a total of 28 participants across the 13 Surnames
D had a total of 16 participants across the 6 surnames
E had a total of 10 participants across the 5 surnames

I have inquired about, but have not received an answer for, what the other
surnames are. I was curious about whether they are ones that show up with
kinship relations or in the same geographic areas as our WEBBs

Blair also looked at the frequency of values obtained for each DYS#. I have
underlined those values which represent the most common result for that DYS#

For example, the first number in the table above is the value obtained at
DYS#393. The value 13 occurs in 80.52% of Blair's DNA samples, while 14 occurs
in only 9.45% of his samples.
DYS# 390 22 occurs in only 13.35% while 24 occurs in 43.80%
DYS# 19(394) has a value of 14 69.62% of the time, while it has a value of 15
20.49% of the time
DYS#391 has a value of 11 53.25% of the time, and a value of 10 42.71% of the
time
DYS# 385a has a value of 11 61.69% of the time and a value of 13 only 11.11%
of the time
DYS#385b has a value of 14 56.64% of the time and of 13 only 6.38% of the
time
DYS#426 has a value of 12 70.92% of the time, while 11 occurs 28.21 of the
time.
DYS#388 has a value of 12 72.51% of the time, of 14 12.48% of the time, but
of 13 only 8.08% of the time.
DYS# 439 has a value of 12 47.40% of the time, of 11 31.46% of the time, but
on 12.12% of the time does one get a value of 13
DYS# 389-1 has a value of 13 68.11% of the time, of 12 19.34% of the time,
and of14 11.54% of the time.
DYS# 392 has a value of 13 63.49% of the time, and of 11 25.32% of the time.
DYS# 389-2 has a value of 29 50.94% of the time, and of 30 21.14% of the
time.

None of the values obtained so far in our 12 marker kits are extremely
unusual.

WEBB 25 marker strings (6 unique)

Blair's study found 421 distinct marker combinations, 74 of which had
multiple participants (225 in the 74 strings). Only TWO (2) 25 marker strings had
multiple surnames and there were a total of 4 participants in these 2 strings
(i.e., 2 surnames for each of 2 strings)

NONE of the WEBB results match the two 25 marker strings with multiple
surnames.

With respect to our 25 markers and the occurrence of values, we have some
unusual results on the following DYS#:

447 one instance of a value of 22 (4.01%) and
3 (matching) participants with a value of 27 (1.92%).

464a one instance of value of 12 (5.24%) & this is the same fellow with the
unusual 447 marker value
3 (matching) participants with a value of 14 (3.14%)
NONE of our samples so far match THE most common marker value for
this DYS

464b one instance of a value of 14 (1.92%) and it's the same guy who was
unusual on 447 & 464a

464c one instance of a value of 14 (0.52%) & yes same guy
NONE of our samples come from THE most common marker value for
this DYS#

464d one instance of a value of 15 (1.05%) & yes same guy

This guy with all the weird values resembles a pair of 12/12 matching
participants on the 12 marker values, although he doesn't match. These 3 are the
ONLY samples with a value of 22 in DYS# 390, which occurs in only 13.35% of
Blair's sample.
The three match on 385a but are one step off on 385b (which more quickly
mutates than 390). 2 at 13 (6.28%) and one at 14 -- THE most common at 56.64%
One step off on DYS#388 (2 at 14 - 12.48%, 1 at 13--8.08%)
One step off on 439 (another more rapidly mutating) 2 at 12 Most common
(47.4%) and one off at 11 (31.46%)
One off at 389-1 with 2 at with 2 at 13 (MOST common 68.11%) and the one at
12 (19.34% 2nd most common)
One off at 389-2 -- 2 at 29 (MOST common at 50.94%) and the one at 28 (3rd
most common at 16.88%) (ALL others are 1st or 2nd most common value here)

The three matching participants are 25/25 matches in 2 cases and a 24/25 one
step (as I understand the term) match in the third. The DYS# 458 value
varies: 2 have 17 (the most common at 31.59%) and the other has a value of 16
(20.77%)

Haplogroup Info

2 who match 25/25 ALL the one step and two step mutation matches and most
of the 3 & 4 step ones show R1B. One 3 step mutation shows Indonesia (O2) and
one 4- step shows R1a.

The fellow who matches the above 24/25 has the same general results, with the
same 2 oddities.

2 12/12 matches have 3 & 4 step matches only ALL 3 and MOST 4 step are I with
on e 4 step G

Participant #6
Exact matches, 1-step & 2-step matches ALL R1B, ALL but ONE 3-step R1b and
the exception is O2.
ALL but one 4-step R1B, and the exception is P

Participant #7
ALL exact, one-step, & 3-step matches R1b
All but one 2-step R1b, and the exception is O2
ALL but one 4-atep match R1b, and the exeption is R1

Participant #8
ALL exact & 1-step matches R1B
ALL but one 2-step R1B and the exeption is O2
THREE step matches mostly R1B, but one P, and 2 R1 matches
4-step mostly R1b, but 6 R1 ands 1 R1a

PArticipant #9
All exact & one-step matches R1b
2-step mostly R1b but one P
3-step mostly R1b but one O2
4-step mostly R1b, but one N & 2 R1

Participant #10 [This is the guy with the unusual values in the DYS#s 7 NOTE
that the 12/12 pair he is most like has similar results.]

ALL one step I
2-step MOSTLY I, one I1b
3-step MOSTLY I, two I1b
4-step MOSTLY I, 2 C3, 4 G, 2 I1b, 1 Q

Participant #11 Kit in lab at present



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Yvette White
Independant Tupperware Consultant
www.my.tupperware.com/ylwhite
email



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